Results 71 to 80 of about 14,746 (241)

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

open access: yesAdvanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey   +6 more
wiley   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

open access: yesAdvanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng   +6 more
wiley   +1 more source

Production of English interdental fricatives by Dutch, German, and English speakers [PDF]

open access: yes, 2010
Non-native (L2) speakers of English often experience difficulties in producing English interdental fricatives (e.g. the voiceless [θ]), and this leads to frequent substitutions of these fricatives (e.g. with [t], [s], and [f]).
Hanulikova, A., Weber, A.
core   +1 more source

Materials for Suppressed Triplet‐Polaron Quenching in Efficient and Long‐Lifetime Phosphorescent OLEDs

open access: yesAdvanced Optical Materials, EarlyView.
We performed a computational screening of phosphorescent emitters and charge transporters for OLEDs to identify combinations that minimize triplet‐polaron quenching, a major cause of efficiency loss and short operational lifetimes, especially in blue OLEDs. Our results reveal key design rules and highlight emitter‐transporter pairs that strongly reduce
Clint van Hoesel   +2 more
wiley   +1 more source

Prosodic description: An introduction for fieldworkers [PDF]

open access: yes, 2008
This article provides an introductory tutorial on prosodic features such as tone and accent for researchers working on little-known languages. It specifically addresses the needs of non-specialists and thus does not presuppose knowledge of the phonetics ...
Himmelmann, N. P., Ladd, D. R.
core  

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

West Slavic accentuation [PDF]

open access: yes, 2010
At the time of the earliest reconstructible dialectal divergences, which belong to the Late Middle Slavic period of my chronology (stages 7.0 - 8.0 of Kortlandt 1989a, 2003, 2008), the West Slavic languages represented the most conservative part of the ...
Kortlandt, Frederik H. H.
core  

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

open access: yesAdvanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob   +12 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

The distribution of trimoraic syllables in German and English as evidence for the phonological word [PDF]

open access: yes, 2013
In the present article I discuss the distribution of trimoraic syllables in German and English. The reason I have chosen to analyze these two languages together is that the data in both languages are strikingly similar.
Hall, Tracy A.
core  

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