Results 261 to 270 of about 16,242,106 (337)

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Transient Andes orthohantavirus RNA detection in an asymptomatic healthcare worker following indirect exposure during hospital care of an imported case, the Netherlands, 2026. [PDF]

Euro Surveill
Tostmann A, Brilman A, Smits L, Huizer B, Reusken C, Te Wierik M, Ruijs H, Geurts van Kessel C, Mattijssen M, Tingen-Wieland M, Coenen-Bouwman O, McCall M, Ruizendaal E, van Schalen I, Veldkamp KE, van Mansfeld R, van der Eijk A, Wertheim HF, Rovers CP.   +18 more
europepmc   +1 more source

Toward Objective Anal Cancer Screening: From Swab‐Based Genome‐Wide Methylation Marker Discovery to Novel Test Development

International Journal of Cancer, EarlyView.
ABSTRACT Anal high‐grade squamous intraepithelial lesions (HSIL:AIN2/3) are precursors to anal cancer, and early detection and treatment through screening is crucial for effective cancer prevention. Current guidelines recommend anal swab‐based screening and highlight the need for objective biomarkers to improve risk stratification.
Kirsten Rozemeijer, Jürgen Claesen, Fernando Dias Gonçalves Lima, Albertus T. Hesselink, Phoebe Klingers, Timo ter Braak, Yara van den Burgt, Chris J. L. M. Meijer, Jan M. Prins, Henry J. C. de Vries, Mark A. van de Wiel, Renske D. M. Steenbergen   +11 more
wiley   +1 more source

Medical Education and Practice at Early Juntendo During the First Three Generations of Directors: Analysis from the Standpoint of History of Medicine. [PDF]

Juntendo Med J
Sakai T.
europepmc   +1 more source

Urinary and Faecal Amino‐Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study

International Journal of Cancer, EarlyView.
ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman, Elsa L. S. A. van Liere, Animesh Acharjee, Sudip Mondal, Eduard A. Struys, Andreas Antoniadis, Jasmijn E. B. de Boer, Shivra R. Siriram, Abdellatif Bakkali, Sofie Bosch, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Manon C. W. Spaander, Tim G. J. de Meij, Evelien Dekker, Dewkoemar Ramsoekh, Nanne K. H. de Boer   +18 more
wiley   +1 more source

Loss to follow-up in patients diagnosed with or treated for low- and high-grade squamous intraepithelial lesions: A comparison of general practitioner- and gynecologist-led surveillance. [PDF]

Acta Obstet Gynecol Scand
van de Kam L, Siebers A, Bekkers R, van Hamont D, Piek J.   +4 more
europepmc   +1 more source

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

International Journal of Cancer, EarlyView.
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea, Youlia Kirova, Radu Iulian Mitrica, Mihaela Badea, Pierre Loap   +4 more
wiley   +1 more source

Adapting Clinical Event Annotation to Dutch Primary Care: An Event Annotation Framework for Post-Acute Infection Syndromes

Mazzucato S, Leeuwenberg A, van Doorn S, van Rosmalen J, Slurink IAL.   +4 more
europepmc   +1 more source

SARS-CoV-2 testing uptake and its determinants in six ethnic groups living in Amsterdam, the Netherlands: a registry-based study within the HELIUS cohort. [PDF]

Eur J Public Health
Campman SL, Boyd A, van Wilgen N, Chilunga FP, Coyer L, Schinkel J, Agyemang C, Galenkamp H, Koopman ADM, Koopsen J, Welkers M, Stronks K, Prins M.   +12 more
europepmc   +1 more source

Introducing cardiology in numbers. [PDF]

Neth Heart J
van der Harst P.
europepmc   +1 more source