Results 101 to 110 of about 2,567,418 (399)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Blade performance prediction model coupled autoencoder with multi-source data fusion strategy
Engineering Applications of Computational Fluid MechanicsThe use of artificial intelligence to develop data-driven aerodynamic performance prediction models has recently become a research hotspot, as it offers significant advantages in computational speed and cost compared to traditional wind tunnel ...
Ruoyu Chen +7 more
doaj +1 more source
Children and Alaska’s Permanent Fund Dividend: Reasons for Rethinking Parental Duty [PDF]
, 2017 Alaska’s Permanent Fund Dividend (Dividend) is an annual payment to eligible residents derived from state investment earnings on mineral royalties. Since 1982, the Dividend has averaged a payout of approximately $1,000 annually.
Kozminsky, Eli
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The “Peripheral Plaintiff”: Duty Determinations in Take-Home Asbestos Cases [PDF]
, 2012 Since the 1970s, litigation concerning the dangers of asbestos in the workplace has transformed from a few workers’ compensation claims to hundreds of thousands of lawsuits against companies in nearly every industry. While the typical plaintiff in these
Kotlarsky, Yelena
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
The Resurrection of the Duty to Inquire After Therasense v. Becton, Dickinson & Co. [PDF]
, 2009 Balancing a duty to a tribunal and a duty to a client can paralyze a lawyer. The task raises difficult questions about how to reconcile competing obligations as an advocate and as an officer of the court.
Woolard, Brandee
core +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
A Dichotomy of Conflicting Duties [PDF]
, 2016 This paper explores the dichotomy of a soldier’s conflicting duties found in contemporary conflicts such as Iraq or Afghanistan. These two conflicting duties, the traditional duty of kill-destroy and the mutually exhaustive duty of help-build, often ...
Montrose, Jeff
core