Results 101 to 110 of about 534,695 (315)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Duty drawbacks, competitiveness, and growth - are duty drawbacks worth the hassle? [PDF]
Many countries use duty drawbacks on exports, yet they have been given little attention in the literature and there is no consensus whether countries should embrace or abandon them.
Ianchovichina, Elena
core
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Implementing the Duty Trip Support Application [PDF]
We are in the process of developing an agent and ontology-based Duty Trip Support application. The goal of this paper is to consider issues arising when implementing such a system.
Marcin Paprzycki +5 more
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Untitled #66 from Tour of Duty, 1999 [picture] /
Title from inscription.; Published title is: "American transport helicopter, Atauro Island, 1999" in Tour of Duty.; Photographer's signature below photograph and on verso lower right.; Also available in an electronic version via the Internet at: http ...
Sleeth, Matthew, 1972-
core
The study students Veiws about faculty academic Advising and consulting duties in k erman university of medical sciences in second semester in 2006 [PDF]
Background & Objective : Consultation is an effective factor in solving students problems Providing insufficient guidance and consultation may prevent achieving educational goals This study was conducted to evaluate students points of view about faculty ...
Ashraf Adhami, Sakineh Mohammad Alizadeh
doaj
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source

