Results 61 to 70 of about 6,504 (256)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Scientific World Journal, 2014 Energy efficiency is an important design paradigm in Wireless Sensor Networks (WSNs) and its consumption in dynamic environment is even more critical. Duty cycling of sensor nodes is used to address the energy consumption problem.
Adnan Noor Mian +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
A Low Power Consumption Algorithm for Efficient Energy Consumption in ZigBee Motes
Sensors, 2017 Wireless Sensor Networks (WSNs) are becoming increasingly popular since they can gather information from different locations without wires. This advantage is exploited in applications such as robotic systems, telecare, domotic or smart cities, among ...
Daniel Vaquerizo-Hdez +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A Cross-Layer Approach to Minimize the Energy Consumption in Wireless Sensor Networks
International Journal of Distributed Sensor Networks, 2013 Energy efficiency represents one of the primary challenges in the development of wireless sensor networks (WSNs). Since communication is the most power consuming operation for a node, many current energy-efficient protocols are based on duty cycling ...
Luca Catarinucci +6 more
doaj +1 more source
Analytical Model for the Duty Cycle in Solar-Based EH-WSN for Environmental Monitoring
Sensors, 2018 A technology drift is currently taking place from traditional battery-powered sensor networks, which exhibit limited lifetime, to the new Energy-Harvesting Wireless Sensor Networks (EH-WSN), which open the way towards self-sustained operation.
Sebastià Galmés, Soledad Escolar
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
IEEE AccessEvent-driven Underwater Acoustic Sensor Networks (UASNs) face the critical challenge of minimizing event-reporting delay while maintaining energy efficiency in resource-constrained underwater environments.
Slavica Tomovic +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source