Results 101 to 110 of about 373,440 (285)

Quantum Arrival and Dwell Times via Idealised Clocks

, 2012
A number of approaches to the problem of defining arrival and dwell time probabilities in quantum theory make use of idealised models of clocks. An interesting question is the extent to which the probabilities obtained in this way are related to standard
A. K. Hashagen, D. A. Downs, H. Goldstein, J. J. Halliwell, J. M. Yearsley, J. Munoz, M. V. Berry, P. van Baal, R. S. Mayato   +8 more
core   +1 more source

Quantum Reflection and Dwell Times of Metastable States [PDF]

Physical Review Letters, 2007
The concept of phase and dwell times used in tunneling is extended to quantum collisions to derive a relation between the phase and dwell time delays in scattering. This relation can be used to remove the near threshold s-wave singularities in the Wigner-Eisenbud delay times and amounts to an extension of the concept of quantum reflection to strong ...
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of Carriage Crowding Level on Bus Dwell Time: Modelling and Analysis

Journal of Advanced Transportation, 2020
This paper develops two types of estimation models to quantify the impacts of carriage crowding level on bus dwell time. The first model (model I) takes the crowding level and the number of alighting and boarding passengers into consideration and ...
Yiming Bie, Yunhao Wang, Le Zhang
doaj   +1 more source

Implications of the Klein tunneling times on high frequency graphene devices using Bohmian trajectories

, 2019
Because of its large Fermi velocity, leading to a great mobility, graphene is expected to play an important role in (small signal) radio frequency electronics. Among other, graphene devices based on Klein tunneling phenomena are already envisioned.
Colomés, Enrique, Oriols, Xavier, Pandey, Devashish, Villani, Matteo, Zhan, Zhen   +4 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source