Results 171 to 180 of about 83,033 (299)

Evolving Role of Negative Pressure Wound Therapy with Instillation and Dwell Time (NPWTi-d-) in Management of Trauma and Orthopaedic Wounds: Mechanism, Applications and Future Perspectives. [PDF]

Indian J Orthop, 2023
Saini R, Jeyaraman M, Jayakumar T, Iyengar KP, Jeyaraman N, Jain VK.   +5 more
europepmc   +1 more source

1084 poster RADIOBIOLOGICALLY EVALUATED DWELL TIME MODULATION RESTRICTION IN HIPO OPTIMIZED HDR PROSTATE BRACHYTHERAPY IMPLANTS [PDF]

, 2011
Milickovic, N, Baltas, D, Mavroidis, P, P. Mavroidis, V. Kefala, N. Zamboglou, Papanikolaou, N, Zamboglou, N, N. Milickovic, Karabis, A, A. Karabis, N. Papanikolaou, Katsilieri, Z, Kefala, V, D. Baltas, Z. Katsilieri   +15 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Ethane groups modified DNA nanopores to prolong the dwell time on live cell membranes for transmembrane transport. [PDF]

Front Chem, 2023
Li Y, Chen X, Lv C, Cheng Y.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Is There a Wound Recontamination by Eluates with High Bacterial Load in Negative-Pressure Wound Therapy with Instillation and Dwell Time? [PDF]

Plast Reconstr Surg, 2023
Stichling M, Wiessner A, Kikhney J, Gatzer R, Müller M, Scheuermann-Poley C, Moter A, Willy C.   +7 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dwell Time Prolongation and Identification of Single Nucleotides Passing through a Solid-State Nanopore by Using Ammonium Sulfate Aqueous Solution. [PDF]

ACS Omega, 2023
Yanagi I, Akahori R, Takeda KI.
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

Complication and Dwell Time of Neonatal Peripheral Venous Catheters with and without Splint: A Descriptive, Correlational, and Prospective Study. [PDF]

Iran J Nurs Midwifery Res
Shirdel S, Farahani AS, Nasiri M, Valadkhani S, Qadimi A, Varzeshnejad M.   +5 more
europepmc   +1 more source