Results 41 to 50 of about 631,178 (293)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Marginal microleakage of newly synthesized nanostructured biomaterials based on active calcium silicate systems and hydroxyapatite [PDF]

Stomatološki glasnik Srbije, 2015
Introduction Calcium silicate cements can be successfully used for the treatment of root perforations due to their exceptional biological and sealing properties.
Petrović Violeta, Opačić-Galić Vanja, Dželetović Bojan, Jokanović Vukoman, Živković Slavoljub   +4 more
doaj  

In vitro study of the periapical sealing ability of three root canal sealing cement

SRM Journal of Research in Dental Sciences, 2019
Objective: The objective of this study was to determine the sealing ability of different root canal cement: resin AH Plus®, calcium hydroxide Sealapex®, and eugenol zinc oxide Pulp Canal Sealer® by measuring the apical penetration of a dye.
Ignacio Barbero-Navarro, Maria Esther Irigoyen-Camacho, Antonio Castano-Seiquer, Marco Antonio Zepeda-Zepeda, Francisco Martins, Paulo Mauricio   +5 more
doaj   +1 more source

A comparative evaluation of microleakage between resin-modified glass ionomer, flowable composite, and cention-N in Class V restorations: A confocal laser scanning microscope study

Journal of Pharmacy and Bioallied Sciences, 2021
Background: Microleakage is a concern while restoring cervical lesions. Many products have attempted to minimize the interfacial gap between the tooth and restoration, the main pathway of microleakage.
Krishnan Venugopal, L Krishnaprasad, V P Prabath Singh, Arjun B Ravi, Kaushik Haridas, Drisya Soman   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Effect of gravity and capillarity on human saliva penetration in coronally unsealed obturated root canals

Saudi Dental Journal, 2012
Aim: The purpose of this study was to evaluate the effect of gravity and capillarity on penetration of human salivary bacteria into the entire length of obturated root canals, and to demonstrate the dye penetration configuration.
Kasra Karamifar, Akbar Khayat, Sara Mogharrabi, Yasaman Rajaei, Mohammad Ali Saghiri   +4 more
doaj   +1 more source

Comparative Evaluation of the Marginal Sealing Ability of two Commercially Available Pit and Fissure Sealants [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: The occlusal surfaces of the teeth usually have pits and fissures which provide a good environment for demineralization with minimal salivary access and make them caries prone.
Lakshmi Priya Sridhar, Joyson Moses, Bollam Nammalwar Rangeeth, Subramanian Sivakumar   +3 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Comparing the sealing properties of mineral trioxide aggregate and an experimental ceramic based root end filling material in different environments

Indian Journal of Dental Research, 2013
Background: An apical seal is an important factor in achieving success in surgical endodontics. Aim: The purpose of this study was to compare the sealing properties of mineral trioxide aggregate (MTA) with a new ceramic based root end filling material ...
Seyed Mohsen Hasheminia, Sam Loriaei Nejad, Omid Dianat, Jalil Modaresi, Faranak Mahjour   +4 more
doaj   +1 more source