Results 71 to 80 of about 1,262,259 (305)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Adsorption and magnetic removal of neutral red dye from aqueous solution using Fe3O4 hollow nanospheres

, 2010
Fe3O4 hollow nanospheres were prepared via a simple one-pot template-free hydrothermal method and were fully characterized. These magnetic spheres have been investigated for application as an adsorbant for the removal of dye contaminants from water ...
Chen Guo, Iram, Mahmood, Guo, Chen, Yueping Guan, Ahmad Ishfaq, Guan, Yueping, Ishfaq, Ahmad, Liu, Huizhou, Mahmood Iram, Iram, M, Huizhou Liu   +10 more
core   +1 more source

Using Eggshell in Acid Orange 2 Dye Removal from Aqueous Solution

علوم بهداشتی ایران, 2015
Background and purpose: Generated dye wastewater by the textile industry is usually toxic, non-biodegradable and resistant in the environment. Eggshell is one of the inexpensive material and for the reason the vesicular structures can be used as a proper
Ahmad Reza Yari, Gharib Majidi, Mehdi Tanhaye Reshvanloo, Mohsen ansari, Shahram Nazari, Meysam Emami Kale Sar, Mohammad Khazaei, Maryam Sadat Tabatabai-Majd   +7 more
doaj  

Removal of cationic dyes by kaolinite

Microporous and Mesoporous Materials, 2009
The removal of cationic dyes such as maxilon yellow 4GL (MY 4GL) and maxilon red GRL (MR GRL) on kaolinite from aqueous solutions has been studied according to the adsorption method. The adsorbed amount of dyes on kaolinite surface was investigated as a function of pH, ionic strength, temperature, acid activation, and calcination temperature.
Hamdi Karaoǧlu, M., Doğan, Mehmet, Alkan, Mahir   +2 more
openaire   +2 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Caracterização e aplicação de adsorvente para a remoção de corantes de efluentes têxteis em batelada e colunas de leito fixo [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia QuímicaA remoção de corantes presentes em efluentes industriais tem recebido enorme atenção nos últimos anos.
Vasques, Andressa Regina
core  

Assessing the efficiency of Fe:TiO2 nanoparticles in removal of Cat Blue 41 using sunlight irradiation in aqueous media using Response surface method (RSM) [PDF]

محیط زیست و مهندسی آب, 2016
Nowadays, protecting environment, especially aqueous medium is a crucial task in modern world. Because of their nature, dyes have not only negative impacts on the aesthetic aspects of the environment, but also result in serious biological and chemical ...
Yahya Zandsalimi, Behzad Shahmoradi, Afshin Maleki, K. Byrappa   +3 more
doaj  

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source