Results 171 to 180 of about 24,634 (294)

Modeling of dynamic responses of arresting gear and its sensitivity study based on BP neural network optimized by Whale optimization algorithm. [PDF]

Sci Rep
Deng Q, Wang J, Gai J, Jian Y, Wang Y, Zheng M.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Misspecified models create the appearance of adaptive control during value-based choice. [PDF]

Commun Psychol
Ritz H, Frömer R, Shenhav A.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

An Energy-Efficient Gas-Oil Hybrid Servo Actuator with Single-Chamber Pressure Control for Biomimetic Quadruped Knee Joints. [PDF]

Biomimetics (Basel)
Yao M, Hua Z, Qian H.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Cloud-edge computing based dual access control scheme for IoV data

Tongxin xuebao
To address the security threats to confidentiality and integrity of shared data in the Internet of vehicles (IoV), a distributed dual access control scheme with key escrow-free and dynamic data integrity verification for vehicle-road-cloud data sharing ...
ZHANG Jiawei, ZHAO Yifan, YANG Yanbo, JIANG Qi, LI Teng, LI Xinghua, MA Jianfeng   +6 more
doaj  

Neural basis of concurrent deliberation toward a choice and confidence judgment. [PDF]

Nat Neurosci
Vivar-Lazo M, Fetsch CR.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Suspension dynamics: From accumulation to instability

Science Talks, 2022
openaire   +1 more source