Results 41 to 50 of about 273,415 (267)
ESC Heart FailureAims Suboptimal device programming is frequent in non‐responders to cardiac resynchronization therapy (CRT). However, the role of device optimization and the most appropriate technique are still unknown.
Előd‐János Zsigmond +9 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
()- model and counting algorithms in dynamic distributed systems
International Journal of Distributed Sensor Networks, 2018 With the advance in mobile network-based systems, dynamic system has become one of the hotspots in fundamental study of distributed systems. In this article, we consider the dynamic system with frequent topology changes arising from node mobility or ...
Zhiwei Yang +4 more
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Sensitivity-Based Change Detection for Dynamic Constrained Optimization
IEEE Access, 2020 In dynamic constrained optimization, changes may occur in either the objective function or constraint functions, or both. However, although research on dynamic optimization has been growing significantly, it is centered mainly around unconstrained ...
Noha Hamza, Ruhul Sarker, Daryl Essam
doaj +1 more source
Dynamical modelling of a genetic algorithm [PDF]
Signal Processing, 2006 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Eduardo José Solteiro Pires +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Exo-structures and domotic algorithms for dynamic architecture
Ain Shams Engineering JournalPhysics, Architecture, Design, and Engineering will renew how buildings interact with their surroundings. An extra layer must be performed between the context and the building to create a new paradigm for Dynamic Architecture.
Samuel Aguilar Posadas +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source