Results 111 to 120 of about 5,686,092 (302)

Dynamic competition between a ligand and transcription factor NusA governs riboswitch-mediated transcription regulation. [PDF]

Proc Natl Acad Sci U S A, 2021
Chauvier A, Ajmera P, Yadav R, Walter NG.   +3 more
europepmc   +1 more source

The dynamic competition of Chinese synonyms over a century

Humanities & Social Sciences Communications
When synonyms coexist in a synset (synonymous set), they often compete with one another in language use. This study examines Chinese synonym competition over a century using the Google Books Ngram Corpus (GBNC) and Chinese Open Wordnet (COW) as the data ...
Shan Wang, Yichi Wang, Haodi Zhang
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

MCDF-Net: Dynamic Adaptive Network Based on Modal Competition and Dual Encoder Feature Fusion for Remote Sensing Image Target Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Remote sensing image object detection, leveraging the complementary characteristics of infrared and RGB imaging, represents an effective approach for achieving all-weather detection.
Yuanjie Zhi, Yushuo Qi, Zhi Yang, Wenkui Hao, Mingyang Ma, Shaohui Mei   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy. [PDF]

J Virol, 2021
Pelz L, Rüdiger D, Dogra T, Alnaji FG, Genzel Y, Brooke CB, Kupke SY, Reichl U.   +7 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Invariance of Competition Outcomes in Hypergraph Competitive Dynamics

CoRR
Winner-take-all (WTA)--type selection is a fundamental mechanism in networked competition, yet its dependence on higher-order interactions remains insufficiently understood. We study a Lotka--Volterra competitive dynamics on higher-order networks, where classical pairwise inhibition is augmented by multi-way interaction terms induced by hyperedges of ...
Qi Zhao, Shaoxuan Cui, Baolin Zhang, Junwei Du, Yuanshi Zheng   +4 more
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source