Results 131 to 140 of about 2,968,753 (303)

Future connections: Implications for connectedness strategy, pedagogy and capability in higher education

, 2019
This chapter reviews and discusses the key findings that emerged from the ten case studies of connectedness learning practice, considering the current connectedness capabilities of higher education students and recent graduates, the potential for using ...
Bridgstock, R., Bridgstock, Ruth S, Tippett, N., Tippett, Neil   +3 more
core   +1 more source

Dynamics of Green and Conventional Bonds: Hedging Effectiveness and Sustainability Implication

International Journal of Financial Studies
This research examines the challenges of issuing green bonds due to a lack of established benchmarks. We compare regional differences between the U.S.
Rihab Belguith
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamic analysis of the relationship between exchange rates and oil prices: a comparison between oil exporting and oil importing countries

Humanities & Social Sciences Communications
Addressing the interconnectedness of oil prices and foreign exchange rates poses a substantial challenge and raises significant questions within economic research.
Shiying Chen, Bisharat Hussain Chang, Hu Fu, ShiQi Xie   +3 more
doaj   +1 more source

Quantile Connectedness Amongst Green Assets Amid COVID-19 and Russia–Ukraine Tussle

Economies
With the advent of greening the global economy and the introduction of green financial assets, this study examines the connectedness and spillover effect of green assets using a QVAR approach focusing on the average connectedness and connectedness under ...
Ayesha Rehan, Wahbeeah Mohti, Paulo Ferreira   +2 more
doaj   +1 more source

Dynamic connectedness between NFTS and market sentiment

, 2022
I study the dynamic return and volatility connectedness between Non-Fungible Tokens (NFTs) and Market Sentiment from May 2018 to June 2022 using a Time-Varying Parameter Vector Autoregression (TVP-VAR) model. I find that certain NFT segments, such as Art, Collectibles, Metaverse, Games, and Utilities, are relatively independent from the Market ...
openaire   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source