Results 101 to 110 of about 19,992 (204)

Christian Bohr. Discoverer of Homotropic and Heterotopic Allostery

Acta Physiologica, Volume 241, Issue S734, July 2025.
ABSTRACT This essay recounts and revisits the scientific contributions of Christian Bohr, highlighting his pivotal role in discovering allostery about 120 years ago. Bohr's meticulous experimentation led to identifying two distinct forms of allostery: homotropic (single‐ligand) and heterotropic (multi‐ligand), the latter widely recognized as the Bohr ...
Niels Bindslev
wiley   +1 more source

Loss of wall stress homeostasis in ascending thoracic aortic aneurysm: histomorphometric insights into patient variants

The Journal of Physiology, Volume 603, Issue 14, Page 3899-3922, 15 July 2025.
Abstract figure legend Dynamic interplay between the extracellular matrix (ECM) and vascular smooth muscle cells (VSMCs) in the medial layer of ascending thoracic aortic aneurysms (ATAA) associated with two variants: thickening (hypertrophic) and thinning (hypotrophic) aneurysm remodelling.
Berta H. Ganizada, Koen D. Reesink, Shaiv Parikh, Pepijn J. M. H. Saraber, Jack P. Cleutjens, Austin Isabella, Mathilde Q. E. Krebbekx, Armand M. Jaminon, Cecile F. M. Maassen, Mitch J. F. G. Ramaekers, Bart Spronck, Koen van der Laan, Rory R. Koenen, Roberto Lorusso, Jos G. Maessen, Elham Bidar, Leon J. Schurgers   +16 more
wiley   +1 more source

Wearable Hyperspectral Photoplethysmography Allows Continuous Monitoring of Exercise‐Induced Hypertension

Advanced Science, Volume 12, Issue 22, June 12, 2025.
A wearable hyperspectral photoplethysmography (HS‐PPG) is reported for continuous blood pressure (BP) monitoring. The HS‐PPG module integrates an ultrathin double‐folded solid immersion grating microspectrometer (DFSIG‐µSPEC), achieving a high spectral resolution of 3.4 nm.
Jung‐Woo Park, Jaehyeok Park, Jaehun Jeon, Seongok Chae, Gi Beom Kim, Geonhui Han, Hyung‐Soon Park, Yong Jeong, Ki‐Hun Jeong   +8 more
wiley   +1 more source

Comparison of Dynamic Contour Tonometry and Goldmann Applanation Tonometry in Relation to Central Corneal Thickness

, 2015
Purpose: In this study we compared the intraocular pressures (IOPs) measured using dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) and investigated the correlation between central corneal thickness (CCT) and IOP.
Min Kim, Si Yoon Park, C. Kim, J. Kim
semanticscholar   +1 more source

Evaluation of Parameters Affecting Measurement Quality of Dynamic Contour Tonometry

Balkan Medical Journal, 2011
Objective: To evaluate factors affecting measurement quality of dynamic contour tonometry (DCT).Material and Methods: Three hundred patients took part in this prospective clinical study.
Vuslat Gürlü, Baran Gencer
doaj  

The Effect of Advancing Age and Intraocular Pressure Injury on Retinal Ganglion Cell Function and Synaptic Connectivity

Aging Cell, Volume 24, Issue 6, June 2025.
The effect of advancing age and intraocular pressure injury on retinal ganglion cell function and synaptic connectivity. While young mice modulate their synaptic input to recover retinal ganglion cell function following injury, older mice compensate by altering their action potential threshold and axon initial segment (AIS) length to increase intrinsic
Vicki Chrysostomou, Sevannah Ellis, Lewis E. Fry, Robert J. Hatch, Eamonn T. Fahy, Katharina C. Bell, Ian A. Trounce, Peter van Wijngaarden, Steve Petrou, Jonathan G. Crowston   +9 more
wiley   +1 more source

In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques. [PDF]

, 2017
Nonhuman primates are the only mammals to possess a true macula similar to humans, and spontaneously develop drusenoid lesions which are hallmarks of age-related macular degeneration (AMD).
Cunefare, David, Farsiu, Sina, Garzel, Laura, Munevar, Christian, Roberts, Jeffrey, Thomasy, Sara, Tieu, Eric, Wong, Brittany, Yiu, Glenn   +8 more
core   +2 more sources

Abnormal wave reflections and left ventricular hypertrophy late after coarctation of the aorta repair [PDF]

, 2017
Patients with repaired coarctation of the aorta are thought to have increased afterload due to abnormalities in vessel structure and function. We have developed a novel cardiovascular magnetic resonance protocol that allows assessment of central ...
Khushnood, Abbas, Muthurangu, Vivek, Pandya, Bejal, Quail, Michael A, Segers, Patrick, Short, Rebekah, Steeden, Jennifer A, Taylor, Andrew M   +7 more
core   +2 more sources

Assessment of graft perfusion and oxygenation for improved outcome in esophageal cancer surgery : protocol for a single-center prospective observational study [PDF]

, 2018
Introduction: The main cause of anastomotic leakage (AL) is tissue hypoxia, which results from impaired perfusion of the pedicle stomach graft after esophageal reconstruction. Clinical judgment is unreliable in determining graft perfusion.
Braeckman, Bart, Ceelen, Wim, Hoorens, Anne, Pattyn, Piet, Van Daele, Elke, Van de Putte, Dirk, Van Limmen, Jurgen, Van Nieuwenhove, Yves, Vanhove, Christian, Varin, Oswald, Willaert, Wouter   +10 more
core   +2 more sources

Corneal biomechanical data and biometric parameters measured with Scheimpflug-based devices on normal corneas [PDF]

, 2018
L
Flaskó, Zsuzsanna, Hassan, Ziad, Lipécz, Ágnes, Módis, László, Németh, Gábor, Szalai, Eszter   +5 more
core   +1 more source