Results 51 to 60 of about 662,525 (267)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A data-driven approach for timescale decomposition of biochemical reaction networks
mSystemsUnderstanding the dynamics of biological systems in evolving environments is a challenge due to their scale and complexity. Here, we present a computational framework for the timescale decomposition of biochemical reaction networks to distill essential ...
Amir Akbari +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Framework for Dynamizing Succinct Data Structures [PDF]
, 2007 We present a framework to dynamize succinct data structures, to encourage their use over non-succinct versions in a wide variety of important application areas. Our framework can dynamize most state-of-the-art succinct data structures for dictionaries, ordinal trees, labeled trees, and text collections.
Ankur Gupta 0003 +3 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Metal structures diagnosis by truncated cone indentation
MATEC Web of Conferences, 2017 The method of the steel structures diagnosis is considered with nondestructive test by truncated cone indentation. Recently, great interest in the nondestructive evaluating of the steel mechanical properties at real structures is developed in many ...
Beskopylny Alexey +2 more
doaj +1 more source
Robustness Analysis of Dynamic Watermarks
Безопасность информационных технологий, 2017 In this paper we consider previously known scheme of dynamic watermarks embedding (Ra- dix-n) that is used for preventing illegal use of software. According to the scheme a watermark is dynamic linked data structure (graph), which is created in memory ...
Ivan V. Nechta
doaj +1 more source
Biophysics and Physicobiology, 2023 Protein functions associated with biological activity are precisely regulated by both tertiary structure and dynamic behavior. Thus, elucidating the high-resolution structures and quantitative information on in-solution dynamics is essential for ...
Shigeyuki Matsumoto +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
PLoS ONE, 2020 We consider the development and fitting of a dynamic model for desalinated water production by a direct-contact membrane distillation (DCMD) unit. Two types of dynamic-model structures, namely, lumped parameter and spatial, were evaluated.
Emad Ali, Jamel Orfi, Abdullah Najib
doaj +1 more source