Results 61 to 70 of about 3,597,207 (294)

Fabrication of Wear-Resistant and Anti-Reflection Surfaces Based on Armor-Protected Nanocone Structures

open access: yesMicromachines
Antireflection surfaces play an indispensable role in modern optics, with extensive applications covering optical windows and other precision optical components.
Haoyu Tian   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Evaluating heat extremes in the UK Climate Projections (UKCP18)

open access: yesEnvironmental Research Letters, 2021
In recent years, UK summer heatwaves have resulted in thousands of excess deaths, with both extreme temperatures and high humidity increasing health risks.
A T Kennedy-Asser   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A High-Performance Perovskite Solar Cell Prepared Based on Targeted Passivation Technology

open access: yesCrystals
Perovskite materials have garnered significant attention in both fundamental research and practical applications owing to their exceptional light absorption coefficients, low fabrication costs, and inherent advantages for thin-film and flexible device ...
Meihong Liu   +15 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-Step Spin-Coating with In Situ Crystallization for Growing 2D/3D Perovskite Films

open access: yesCrystals
Developing perovskite solar cells (PSCs) with both high performance and long-term stability remains a critical challenge and research focus in the field of photovoltaic devices.
Meihong Liu   +15 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Design and Fabrication of Thermopile Infrared Detector Based on Carbon Black Nanoparticle Absorption Layer

open access: yesPhotonics
This study demonstrates a high-performance thermopile infrared detector that incorporates a carbon black nanoparticle (CBNP) absorption layer. To overcome the limitations associated with conventional infrared-absorbing materials—including high cost ...
Cheng Lei   +6 more
doaj   +1 more source

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