Results 41 to 50 of about 227,509 (264)
Dynamic Traffic Network Equilibrium System
Fixed Point Theory and Applications, 2010 We discuss the dynamic traffic network equilibrium system problem. We introduce the equilibrium definition based on Wardrop's principles when there are some internal relationships between different kinds of goods which transported through the same ...
Yun-Peng He +3 more
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Colin Rowe and ' Dynamic Equilibrium'
Cuadernos de Proyectos Arquitectónicos, 2015 In 1944 Gyorgy Kepes published what undoubtless will be his most influential text, "The language of vision". What Kepes tried to do was a guide of grammar and syntax of vision, which allows to face art as purely sensory experience or just visual ...
Pablo López Marín
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
International Journal of Public HealthObjectivesOur objective was to assess morbidity trends in Europe and to classify European countries based on population ageing theories: the compression, expansion and dynamic equilibrium of morbidity.MethodsThe proportions of healthy life years were ...
Jakub Straka +3 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Вестник КазНУ. Серия математика, механика, информатика, 2016 In this paper the technique of analytical determination of internal forces in links of planar mechanisms and manipulators with statically indeterminate structures taking into account the distributed dynamical loads, a dead weight and the operating ...
S. Zhilkibayeva +2 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Dynamic disorder in quasi-equilibrium enzymatic systems. [PDF]
PLoS ONE, 2010 Conformations and catalytic rates of enzymes fluctuate over a wide range of timescales. Despite these fluctuations, there exist some limiting cases in which the enzymatic catalytic rate follows the macroscopic rate equation such as the Michaelis-Menten ...
Srabanti Chaudhury, Oleg A Igoshin
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source