Results 91 to 100 of about 103,223 (292)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Altered static and dynamic effective connectivity in patients with type 2 diabetes mellitus with and without microvascular complications

European Journal of Medical Research
Objective To address critical knowledge gaps in static connectivity studies by characterizing how directional, dynamic effective connectivity reconfigures across brain states in T2DM with and without microvascular complications from a causal perspective,
Kun Wang, Zhizhong Sun, Jiahe Wang, Ziyu Diao, Die Shen, Xuan Huang, Shijun Qiu   +6 more
doaj   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Characterizing Whole Brain Temporal Variation of Functional Connectivity via Zero and First Order Derivatives of Sliding Window Correlations

Frontiers in Neuroscience, 2019
Brain functional connectivity has been shown to change over time during resting state fMRI experiments. Close examination of temporal changes have revealed a small set of whole-brain connectivity patterns called dynamic states. Dynamic functional network
Flor A. Espinoza, Flor A. Espinoza, Victor M. Vergara, Victor M. Vergara, Eswar Damaraju, Eswar Damaraju, Kyle G. Henke, Kyle G. Henke, Ashkan Faghiri, Ashkan Faghiri, Ashkan Faghiri, Jessica A. Turner, Jessica A. Turner, Aysenil A. Belger, Judith M. Ford, Judith M. Ford, Sarah C. McEwen, Sarah C. McEwen, Daniel H. Mathalon, Daniel H. Mathalon, Bryon A. Mueller, Steven G. Potkin, Adrian Preda, Jatin G. Vaidya, Theo G. M. van Erp, Theo G. M. van Erp, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun, Vince D. Calhoun   +29 more
doaj   +1 more source

Dynamic Reconfiguration of Visuomotor-Related Functional Connectivity Networks [PDF]

The Journal of Neuroscience, 2016
Cognitive functions arise from the coordination of large-scale brain networks. However, the principles governing interareal functional connectivity dynamics (FCD) remain elusive. Here, we tested the hypothesis that human executive functions arise from the dynamic interplay of multiple networks.
Brovelli, Andrea, Badier, Jean-Michel, Bonini, Francesca, Bartolomei, Fabrice, Coulon, Olivier, Auzias, Guillaume   +5 more
openaire   +3 more sources

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Quasi-periodic patterns of brain activity in individuals with attention-deficit/hyperactivity disorder

NeuroImage: Clinical, 2019
Individuals with attention-deficit/hyperactivity disorder have disrupted functional connectivity in the default mode and task positive networks. Traditional fMRI analysis techniques that focus on ‘static’ changes in functional connectivity have been ...
Anzar Abbas, Yasmine Bassil, Shella Keilholz   +2 more
doaj   +1 more source

Dynamic functional connectivity of neurocognitive networks in children

Human Brain Mapping, 2016
AbstractThe human brain is highly dynamic, supporting a remarkable range of cognitive abilities that emerge over the course of development. While flexible and dynamic coordination between neural systems is firmly established for children, our understanding of brain functional organization in early life has been built largely on the implicit assumption ...
Hilary A, Marusak, Vince D, Calhoun, Suzanne, Brown, Laura M, Crespo, Kelsey, Sala-Hamrick, Ian H, Gotlib, Moriah E, Thomason   +6 more
openaire   +3 more sources