Results 41 to 50 of about 6,529,952 (255)

Dynamic Brain Connectivity in Resting-State FMRI Using Spectral ICA and Graph Approach: Application to Healthy Controls and Multiple Sclerosis

open access: yesDiagnostics, 2022
Multiple sclerosis (MS) is a neuroinflammatory disease that involves structural and functional damage to the brain. It changes the functional connectivity of the brain between and within networks. Resting-state functional magnetic resonance imaging (fMRI)
Amir Hosein Riazi   +2 more
doaj   +1 more source

Modeling dynamic functional connectivity with latent factor Gaussian processes [PDF]

open access: yes, 2019
Dynamic functional connectivity, as measured by the time-varying covariance of neurological signals, is believed to play an important role in many aspects of cognition.
Li, Lingge   +5 more
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Sample entropy reveals an age-related reduction in the complexity of dynamic brain

open access: yesScientific Reports, 2017
Dynamic reconfiguration of the human brain is characterized by the nature of complexity. The purpose of this study was to measure such complexity and also analyze its association with age.
Yanbing Jia, Huaguang Gu, Qiang Luo
doaj   +1 more source

Resting State fMRI Reveals Diminished Functional Connectivity in a Mouse Model of Amyloidosis [PDF]

open access: yes, 2013
Introduction: Functional connectivity (FC) studies have gained immense popularity in the evaluation of several neurological disorders, such as Alzheimer’s disease (AD). AD is a complex disorder, characterised by several pathological features. The problem
Rafael Delgado Y Palacios   +36 more
core   +2 more sources

EEG Microstates Predict Concurrent fMRI Dynamic Functional Connectivity States [PDF]

open access: yes, 2020
Brain functional connectivity measured by resting-state fMRI varies over multiple time scales, and recurrent dynamic functional connectivity (dFC) states have been identified.
Jorge, Joao   +15 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Dynamics of Intersubject Brain Networks during Anxious Anticipation

open access: yesFrontiers in Human Neuroscience, 2017
How do large-scale brain networks reorganize during the waxing and waning of anxious anticipation? Here, threat was dynamically modulated during human functional MRI as two circles slowly meandered on the screen; if they touched, an unpleasant shock was ...
Mahshid Najafi   +2 more
doaj   +1 more source

Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease

open access: yesNeural Regeneration Research, 2022
Numerous studies have shown abnormal brain functional connectivity in individuals with Alzheimer’s disease (AD) or amnestic mild cognitive impairment (aMCI).
Cui Zhao   +9 more
doaj   +1 more source

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