Results 191 to 200 of about 50,036 (314)

The Mechanism and Design Principles of Serious Games in Enhancing Adolescents' Internet Adaptability. [PDF]

JMIR Serious Games
Gao S, Jia M, Wang W, Hu J, Ma S.
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Editorial: The dark and the light side of gaming, volume II. [PDF]

Front Psychol
de la Hera T, Reer F, Siitonen M.
europepmc   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Time Consistent Pareto Solutions in Common Access Resource Games with Asymmetric Players

In the analysis of equilibrium policies in a dierential game, if agents have different time preference rates, the cooperative (Pareto optimum) solution obtained by applying the Pontryagin's Maximum Principle becomes time inconsistent.
Jesus Marin-Solano, Albert de-Paz, Jorge Navas   +2 more
core  

Logit dynamic for continuous strategy games: existence of solutions

, 2007
We define the logit dynamic in the space of probability measures for a game with a compact and continuous strategy set. The original Burdett and Judd (1983) model of price dispersion comes under this framework. We then show that if the payoff functions
Lahkar, R.
core  

Thinking out of the (Olympic) box: is it time to reconsider permanent hosting for sustainable Olympics? A conceptual review. [PDF]

Front Sports Act Living
Pappous AS.
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Evolution in Symmetric Incomplete Information Games [PDF]

The paper compares two models of evolution in symmetric two-player games with incomplete information. One model postulates that the type of a player is fixed, and evolution works within types. In the other model type-contingent strategies evolve.
Erwin Amann, Alex Possajennikov
core  

Reply to Romano and De Dreu: Why violent extremism cannot be reduced to laboratory games. [PDF]

Proc Natl Acad Sci U S A
Kunst JR, Besta T, Obaidi M.
europepmc   +1 more source