Results 31 to 40 of about 31,073 (263)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Basketball Elements in Physical Education Lessons for Primary School Students
ACROSS, 2022 There are several ways to optimize the training process using various complexes of exercises, dynamic games and much more in physical education in school, including the primary level.
Constantin CIORBĂ
doaj
DEVELOPING MOTOR QUALITIES SPEED AND SKILL USING MOTION GAMES AT FOURTH GRADE LEVEL [PDF]
Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2021 Through this study I want to confirm the need to use dynamic games in physical education classes and to demonstrate the efficiency that movement games have in the development of motor skills.
Benedek Florian
doaj
Tingkat Kesulitan Dinamis Menggunakan Logika Fuzzy pada Game Musik Tradisional Jawa Tengah
Jurnal ELTIKOM: Jurnal Teknik Elektro, Teknologi Informasi dan Komputer, 2021 The culture in Indonesia is very diverse, one of which is traditional songs. However, knowledge of traditional songs is still small. Digital Games can spread knowledge about traditional songs, one of which is Central Javanese traditional songs.
Kadhana Reya Wisinggya +4 more
doaj +1 more source
Robust dynamic cooperative games [PDF]
International Journal of Game Theory, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
BAUSO, Dario, Timmer, J.
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
CONTRIBUTION OF DYNAMIC GAMES AND HANDBALL RESOURCES IN DEVELOPING PSYCHOMOTOR SKILLS FOR III-RD AND IV-TH DEGREE PUPILS [PDF]
Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2018 The research consisted proper application of control samples for manifestations of speed and coordinative skill by specific handball tests. The purpose of this experimental research is to find the best ways to increase the speed and skill motric ...
Petrariu Ileana
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dynamics of three-agent games [PDF]
Journal of Physics A: Mathematical and Theoretical, 2008 We study the dynamics and resulting score distribution of three-agent games where after each competition a single agent wins and scores a point. A single competition is described by a triplet of numbers $p$, $t$ and $q$ denoting the probabilities that the team with the highest, middle or lowest accumulated score wins.
Mungan, Muhittin, Rador, Tonguc
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source