Results 161 to 170 of about 62,130 (264)

Minimum Vertex Cut with Reachable Set (MVCRS) Problem for Suppressing Botnet Propagation in IoT Networks: Complexity and Algorithms. [PDF]

Sensors (Basel)
Yamaguchi S.
europepmc   +1 more source

Relabeling Algorithms on Dynamic Graphs

, 2012
Distributed algorithms executed over dynamic graphs are difficult to study due to the limited knowledge of decentralized algorithms, the uncertainty dynamism in graphs entails, and the myriad of competing and immature models. One particular framework combining relabeling systems and evolving graphs struck us as both elegant and sound [CCF12].
openaire   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

An in-depth analysis of UAV path planning, including procedures, algorithms, optimization models, and emerging challenges. [PDF]

MethodsX
Nafees M, Syeda T, Ali A, Farman H, Tayyab M.   +4 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

TSA-HGNN: a stability-aware multi-scale temporal graph neural network for dynamic community detection. [PDF]

Front Artif Intell
Vusirikkayala G, Madhu Viswanatham V.
europepmc   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Multi-omics and artificial intelligence for precision drug discovery and potential clinical applications. [PDF]

Signal Transduct Target Ther
Liu Y, Zhu K, Peng W, Liu Z, Mao X.
europepmc   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

TGN-MCDS: A Temporal Graph Network-Based Algorithm for Cluster-Head Optimization in Large-Scale FANETs. [PDF]

Sensors (Basel)
Fan X, Yang Y, Zhang S, Cai W.
europepmc   +1 more source