Results 131 to 140 of about 12,139,664 (308)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Dynamic Capabilities and their Indirect Impact on Firm Performance [PDF]
This paper investigates the relationship between dynamic capabilities and firm performance. In particular it addresses the question of whether dynamic capabilities impact directly or indirectly on performance.
Spyros Lioukas +2 more
core
Flows of Knowledge: A Method for Impact Assessment
The Flows of Knowledge evaluation method, as introduced by Meagher, Lyall and Nutley (2008) and described in Edwards and Meagher (2020), provides a framework for assessing the impacts of scientific research on policy and practice.
Evaluating Societal Impact
core +1 more source
EnergiesThis study presents a comprehensive experimental investigation of the mechanical response of the jellyroll and complete Li-ion 18650 Nickel–Cobalt–Alumina (NCA) battery under axial compression, highlighting the effects of strain rate and state-of-charge (
Sigit Puji Santosa, Hafiz Fadillah
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Preparing case studies for impact within SEP (2021-2027)
Every six years, on a rolling basis, Dutch universities and research institutes are evaluated according to the Strategy Evaluation Protocol (SEP).Based on the experiences with the Strategy Evaluation Protocol (SEP) at the Erasmus University Rotterdam as ...
Evaluating Societal Impact
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source