Results 261 to 270 of about 12,139,664 (308)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

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Stochastic Dynamics of Impact Oscillators

Journal of Applied Mechanics, 2004
Abstract The purpose of this work is to develop an averaging approach to study the dynamics of a vibro-impact system excited by random perturbations. As a prototype, we consider a noisy single-degree-of-freedom equation with both positive and negative stiffness and achieve a model reduction, i.e., the development of rigorous methods to ...
Namachchivaya, N. Sri, Park, Jun H.
openaire   +2 more sources

The Impact Dynamics

2010
Together with geological/geophysical studies and laboratory-scale experiments numerical simulations of impacts contribute a great deal to our knowledge of the cratering process. Whereas field studies give information about target conditions and final crater configuration, numerical modeling allow us to follow the evolving process in time and to ...
Valery Shuvalov, Henning Dypvik, Filippos Tsikalas   +2 more
openaire   +1 more source

The Impact of Viscosity on the DNA Dynamics

Physica Scripta, 2001
Summary: We investigate the nonlinear dynamics of a DNA chain affected by the damping associated with the viscosity of a solvent. The dynamics of the DNA chain is described by the Peyrard-Bishop [\textit{M. Peyrard} and \textit{A. R. Bishop}, Phys. Rev. Lett. 62, 2755 ff (1989)] extended model for breather-like coherent excitations. We show that a bell
Zdravković, S., Satarić, M. V.
openaire   +1 more source

An Investigation of the Dynamic System with Impacts

Chaos, Solitons & Fractals, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Błażejczyk-Okolewska, Barbara, Peterka, František   +1 more
openaire   +1 more source

Schizophrenia: Impact on Family Dynamics

Current Psychiatry Reports, 2017
In many societies, family members are now the primary caregivers of mental health patients, taking on responsibilities traditionally under the purview of hospitals and medical professionals. The impact of this shift on the family is high, having both an emotional and economic toll.
Caqueo-Urízar, Alejandra, Rus-Calafell, Mar, Craig, Thomas K.J., Irarrazaval, Matias, Urzúa, Alfonso, Boyer, Laurent, Williams, David R.   +6 more
openaire   +3 more sources

Impact Dynamics for Elastic Membranes

Physical Review Letters, 2006
We study the dynamic response of stretched thin polymeric films following an impact by a rigid sphere. We vary the sphere radius, the impact velocity, and the film tension, and measure the contact time and the maximum deflection of the film during the impact. The response is sensitive to nonlinearities associated with the additional tension provided by
Laurent, Courbin, Antonin, Marchand, Ashkan, Vaziri, Armand, Ajdari, Howard A, Stone   +4 more
openaire   +2 more sources

Dynamic trading policies with price impact

Journal of Economic Dynamics and Control, 2001
In this paper we analyze the optimal policy for a risk averse agent who wants to sell a large block of shares of a risky security in the presence of price impact and transactions costs. Our framework reduces to the standard Merton portfolio problem in the absence of any market frictions.
Hua He, Harry Mamaysky
openaire   +2 more sources