Results 61 to 70 of about 36,870 (217)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
On the Impact of Fair Best Response Dynamics [PDF]
, 2012 In this work we completely characterize how the frequency with which each player participates in the game dynamics affects the possibility of reaching efficient states, i.e., states with an approximation ratio within a constant factor from the price of anarchy, within a polynomially bounded number of best responses.
A. Fanelli +2 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An Investigation into the Design and Analysis of the Front Frame Bumper with Dynamic Load Impact
Engineering ProceedingsThe present study is aimed at upgrading the passenger car’s front inner bumper. The dynamic explicit time-stepping method IMPACT was used to conduct the impact analysis.
B. Gowthama Rajan +6 more
doaj +1 more source
MATEC Web of Conferences, 2017 The problems of optimization of reinforced concrete structures are considered taking into account their properties and features under fire impacts and dynamic loading.
Tampazyan Ashot, Zubareva Svetlana
doaj +1 more source
Mechanical and reactive properties of PTFE/Al/MoO3 composites
Cailiao gongcheng, 2019 PTFE/Al/MoO3 composites with different PTFE concentrations were prepared by mold pressing and sintering. The materials were characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD), in addition, the properties of the composites ...
HUANG Jun-yi +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Experimental study on dynamic mechanical properties and damage law of steel fiber concrete
工程科学学报Investigating the effect of steel fiber blending schemes on the dynamic mechanical properties and damage evolution of concrete is crucial for deep-shaft construction projects.
Yisong YU +4 more
doaj +1 more source
Bruise susceptibilities of kiwifruit as affected by impact and fruit properties
Research in Agricultural Engineering, 2012 Kiwifruit bruise damage is a common postharvest disorder that substantially reduces fruit quality and marketability. Fruit bruise cause tissue softening and make them more susceptible to undesired agents such as diseases-inducing agents.
E. Ahmadi
doaj +1 more source