Results 91 to 100 of about 4,475,198 (252)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Application of Analog Adaptive Filters for Dynamic Sensor Compensation

, 2005
This paper investigates the application of analog adaptive techniques to the area of dynamic sensor compensation, of which there is little reported work in the literature. The case is illustrated by showing how the response of a load cell can be improved
White, Neil M., Jafaripanah, Mehdi, Al-Hashimi, Bashir   +2 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Multiple-objective Load Optimization Control Based on Fuzzy Dynamic Programming

, 2015
Direct load control DLC is one of the important means for demand response in the electricity market. Combined with the features of direct load control strategy, this paper takes electricity benefit increase, systems peak load reduction as well as ...
Chen F(陈凤), Zeng P(曾鹏), Zang CZ(臧传治)   +2 more
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Dynamic Response of Planetary Bearings in a Double Planetary Gear Train with Forward and Reverse Carrier Rotations

Machines
Planetary bearings are critical components in double planetary gear trains. The influence of carrier rotation direction on bearing dynamic behavior remains insufficiently understood, which hinders accurate reliability assessment and optimal design.
Yudong Zhang, Biao Ma, Kun Liu, Liang Yu, Jing Zhang, Run Mao, Hanqiao Sun   +6 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Development of Low-Voltage Load Models for the Residential Load Sector [PDF]

, 2014
A bottom-up modeling approach is presented that uses a Markov chain Monte Carlo (MCMC) method to develop demand profiles. The demand profiles are combined with the electrical characteristics of the appliance to create detailed time-varying models of ...
Kiprakis, Aristides, Collin, Adam J., McLaughlin, Stephen, McLaughlin, Steve; id_orcid, Colin, Adam, Tsagarakis, George, Kiprakis, Aristides E.   +6 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source