Results 91 to 100 of about 280,732 (268)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
LubricantsFor wind turbine applications, there is a cyclic load-varying process between rolling elements and raceways in pitch bearings. This kind of motion can also lead to radial fretting.
Yiming Han +7 more
doaj +1 more source
Dynamic Load Generator: Synthesising dynamic hardware load characteristics
, 2015 In this thesis we proposed and tested a new method for creating synthetic workloads. Our method takes the dynamic behaviour into consideration, whereas previous studies only consider the static behaviour. This was done by recording performance monitor counters (PMC) events from a reference application.
Karlsson, Stefan, Hansson, Erik
openaire +1 more source
Loading device for oncoming dynamic loading
Traktory i sel hozmashiny, 2014 Methods of running and testing of parts, units and aggregates under load in case of transferring required drive torques through them are considered. The method of loading by oncoming drive torques using inertial loaders is theoretically substantiated.
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Competitive Equilibrium in Microgrids with Dynamic Loads
2024 American Control Conference (ACC)In this paper, we consider microgrids that interconnect prosumers with distributed energy resources and dynamic loads. Prosumers are connected through the microgrid to trade energy and gain profit while respecting the network constraints. We establish a local energy market by defining a competitive equilibrium which balances energy and satisfies ...
Zeinab Salehi +4 more
openaire +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Influence of dynamic load and water on energy accumulation and dissipation in sandstone. [PDF]
Sci Rep, 2023 Yang Y +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source