Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Experimental study on deformation characteristics of seasonal subgrade soil under dynamic load. [PDF]
Li D +5 more
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Study on interfacial mechanical properties of bonded pipe joint under dynamic load. [PDF]
Lin Z, Li S.
europepmc +1 more source
A new regularization method for dynamic load identification. [PDF]
Wang L, Huang Y, Xie Y, Du Y.
europepmc +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Design and Development of Miniature Measuring Instrument for Parachute Cords Dynamic Load for Stepless Parachute Opening. [PDF]
Liang W, Zhao X, Wu P, Li Y, Lv S.
europepmc +1 more source
VFFVA: dynamic load balancing enables large-scale flux variability analysis. [PDF]
Guebila MB.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Simulated and measured piezoelectric energy harvesting of dynamic load in tires. [PDF]
Staaf H +10 more
europepmc +1 more source

