Results 91 to 100 of about 2,292,684 (349)

Thermal elastohydrodynamic lubrication of spur gears [PDF]

open access: yes
An analysis and computer program called TELSGE were developed to predict the variations of dynamic load, surface temperature, and lubricant film thickness along the contacting path during the engagement of a pair of involute spur gears.
Cheng, H. S., Wang, K. L.
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Fire responses and resistance of concrete-filled steel tubular frame structures [PDF]

open access: yes, 2010
This paper presents the results of dynamic responses and fire resistance of concretefilled steel tubular (CFST) frame structures in fire conditions by using non-linear finite element method.
Buchanan A. H.   +8 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Performance of TenCate Paving Interlayers in Asphalt Concrete Pavements [PDF]

open access: yes, 2017
As a continued effort of a previously completed project entitled “Performance of TenCate Mirafi PGM-G4 Interlayer-Reinforced Asphalt Pavements in Alaska,” this project evaluated two newly modified paving interlayers (TruPave and Mirapave) through overlay,
Li, Lin, Liu, Jenny, Zhao, Sheng
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Structural characterization of a first-generation articulated-truss joint for space crane application [PDF]

open access: yes
A first-generation space crane articulated-truss joint was statically and dynamically characterized in a configuration that approximated an operational environment.
Laufer, Joseph B.   +4 more
core   +1 more source

Seismic qualification of directional valve [PDF]

open access: yes, 2001
Seismic qualification tests on pneumatically operated directional valve were carried out in the shake table facility in Structural Integrity Division. Determination of the fundamental frequency for directional valve was carried out through exploratory ...
Brahma, KK
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Experimental test of static and dynamic characteristics of tilting-pad thrust bearings

open access: yesAdvances in Mechanical Engineering, 2015
The axial vibration in turbine machine has attracted more and more interest. Tilting-pad thrust bearings are widely used in turbine machines to support the axial load.
Annan Guo   +4 more
doaj   +1 more source

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