Results 131 to 140 of about 992,444 (308)
Finite element analysis using NASTRAN applied to helicopter transmission vibration/noise reduction [PDF]
, 1975 A finite element NASTRAN model of the complete forward rotor transmission housing for the Boeing Vertol CH-47 helicopter was developed and applied to reduce transmission vibration/noise at its source.
Howells, R. W., Sciarra, J. J.
core +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Determination of load sequence effects on the degradation and failure of composite materials [PDF]
A theoretical model was established to predict the fatigue behavior of composite materials, with emphasis placed on predictions of the degradation of residual strength and residual stiffness during fatigue cycling.
Jones, D. L., Yang, J. N.
core +1 more source
Modelling of motion resistance ratios of pneumatic and rigid bicycle wheels [PDF]
, 2013 The motion resistances of 660 mm pneumatic and rigid bicycle wheels of the same rim diameter were measured experimentally using the developed tractor-towed single non-lug narrow wheel motion resistance test rig for traction studies.
Ahmad, Desa +4 more
core
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Human MovementPurpose The study aimed to compare the effects of high-load isometric versus high-load dynamic contrast resistance training on soccer players’ physical performance.
Mohit Dhull +3 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Development of Transmission Error Dynamic Testing Machine for Plastic Gear
Jixie chuandong, 2019 Based on the principle of single flank measurement, a dynamic testing machine for plastic gear transmission error is developed and can simulate the actual working condition of the plastic gear and realize the dynamic measurement of transmission error ...
Zhaoyao Shi +6 more
doaj
Nonlinear maneuver autopilot for the F-15 aircraft [PDF]
A methodology is described for the development of flight test trajectory control laws based on singular perturbation methodology and nonlinear dynamic modeling.
Badgett, M. E. +2 more
core +1 more source