Results 41 to 50 of about 992,444 (308)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Dynamic loading tests for final settling tanks
Dynamic experiments conducted in a pilot scale settling tank at Zurich's wastewater treatment plant (WWTP) are presented. The experiments were carried out with real activated sludge. They showed that vertical perforated walls transverse to the main flow direction are very beneficial particularly for wet-weather flow.
Peter Krebs +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In order to evaluate the fatigue durability of the hybrid vehicle driveline, the load simulation test system is used to simulate the dynamic load spectrum of the vehicle on the actual road.
Kaihua Cheng
doaj
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The wind turbine system in the offshore area will be subjected to the combined action of complex marine environment dynamic loads. At present, there is a certain advantage to using traditional mechanical devices to simulate marine environmental loads. In
Xiaoling Zhang +2 more
doaj +1 more source
Acoustic testing techniques for replicating in-flight dynamic loads [PDF]
Modern weapon systems used on combat aircraft have complex electronic assemblies that are required to operate in a challenging dynamic environment throughout their life cycle. Among the various sources of excitation, aerodynamic noise is considered most significant.
Kobi J, Cohen, Daniella E, Raveh
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Influence of Physical Load on Dynamic Postural Control—A Systematic Replication Study
Dynamic postural control is challenged during many actions in sport such as when landing or cutting. A decrease of dynamic postural control is one possible risk factor for non-contact injuries.
Jessica Heil, Sarah Schulte, Dirk Büsch
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

