Results 81 to 90 of about 992,444 (308)
Load Testing and Analysis of a Large Span Through Simply-Supported Steel Box Arch Bridge
Applied SciencesTo evaluate the true load-bearing capacity and engineering reliability of a large span through a simply supported steel box arch bridge, a load test was conducted on the bridge.
Zhenwei Liu +4 more
doaj +1 more source
Comparison of analysis and experiment for dynamics of low-contact-ratio spur gears [PDF]
Low-contact-ratio spur gears were tested in NASA gear-noise-rig to study gear dynamics including dynamic load, tooth bending stress, vibration, and noise.
Lin, Hsiang Hsi +4 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Thermal elastohydrodynamic lubrication of spur gears [PDF]
An analysis and computer program called TELSGE were developed to predict the variations of dynamic load, surface temperature, and lubricant film thickness along the contacting path during the engagement of a pair of involute spur gears.
Cheng, H. S., Wang, K. L.
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Fire responses and resistance of concrete-filled steel tubular frame structures [PDF]
, 2010 This paper presents the results of dynamic responses and fire resistance of concretefilled steel tubular (CFST) frame structures in fire conditions by using non-linear finite element method.
Buchanan A. H. +8 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Structural characterization of a first-generation articulated-truss joint for space crane application [PDF]
A first-generation space crane articulated-truss joint was statically and dynamically characterized in a configuration that approximated an operational environment.
Laufer, Joseph B. +4 more
core +1 more source
Behaviour of reinforced concrete beam under dynamic loading / Md Rasul Mohamad Nor [PDF]
, 1996 The study of reinforced concrete beam behaviour under dynamic loading as well as static loading with respect to the serviceability and ultimate limits is undertaken A total of four (4) beams with minimum strength of 60 N/mm2 casted, Each beams underwent ...
Mohamad Nor, Md Rasul
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source