Results 91 to 100 of about 7,484,360 (335)

Application of numerical calculation methods in stability analysis of pile foundation under complex foundation conditions

open access: yesNonlinear Engineering
Pile foundation has been widely applied in modern civil engineering due to its excellent performance under complex foundation conditions. However, when subjected to dynamic loads such as waves, tides, and earthquakes, the long-term stability of pile ...
Wang Huimin   +3 more
doaj   +1 more source

On dynamic loads in parallel shaft transmissions. 2: Parameter study [PDF]

open access: yes
Solutions to the governing equations of a spur gear transmission model, developed in NASA TM-100180 (AVSCOM TM-87-C-2), are presented. Factors affecting the dynamic load are identified.
Coy, John J.   +2 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Dynamic Loading and the Problem of Strength

open access: yesМеханика машин, механизмов и материалов, 2010
An analysis of dynamic behavior of the threshold characteristics of rock samples with the macrocrack. Found that for each breed there is an optimal duration of loading, which allows to minimize the costs of fracture.
N.F. Morozov   +2 more
doaj  

Effects of grain size distribution on the initial strain shear modulus of calcareous sand [PDF]

open access: yes, 2015
The soil’s small strain shear modulus, Gmax or G0, is applied in dynamic behavior analyses and is correlated to other soil properties (density and void ratio) for predicting soil dynamic behavior under seismic loadings such as earthquakes, machinery or ...
Haegeman, Wim   +4 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Experimental and Numerical Research on Fracture Properties of Mass Concrete Under Quasi-Static and Dynamic Loading

open access: yesBuildings
The dynamic fracture behavior of mass concrete is crucial to the dynamic analysis and safety evaluation of concrete dams subjected to strong earthquake shocks in the framework of fracture mechanics. In the presented research, cylindrical specimens with a
Yazhou Zhang   +6 more
doaj   +1 more source

Temperature-Induced Shape Memory Characteristics of Epoxy Resin-Based Fabric-Reinforced Composites [PDF]

open access: yes, 2013
Shape memory characteristics of woven glass and carbon fiber fabric reinforced epoxy resin-based composites were assessed in bending mode using a dynamic mechanical analyzer.
Karger-Kocsis, J.
core   +1 more source

Dynamic Load Balancing with Tokens [PDF]

open access: yes2018 IFIP Networking Conference (IFIP Networking) and Workshops, 2018
Efficiently exploiting the resources of data centers is a complex task that requires efficient and reliable load balancing and resource allocation algorithms. The former are in charge of assigning jobs to servers upon their arrival in the system, while the latter are responsible for sharing server resources between their assigned jobs. These algorithms
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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