Results 141 to 150 of about 7,484,360 (335)

A damage-plasticity model for the dynamic failure of concrete

open access: yes, 2011
A constitutive model based on the combination of damage mechanics and plasticity is developed to analyse concrete structures subjected to dynamic loading. The aim is to obtain a model, which requires input parameters with clear physical meanings.
Grassl, Peter   +3 more
core  

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Site Investigations on the Lateral Movement of Skewed Prestressed Concrete Sleepers (PCS) Subjected to Rail Dynamic Loading

open access: yesJournal of Engineering Technology and Applied Physics
Prestressed concrete sleepers (PCS) are crucial for preserving track stability under dynamic train loads. This study compares the dynamic load behavior of a skewed PCS (placed at a minor angle with one rail seat spacing of 0.67 m instead of the ...
C. M. C. J. M. Hilmi Safiuddin   +3 more
doaj   +1 more source

Chemonucleolysis combined with dynamic loading for inducing degeneration in bovine caudal intervertebral discs. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Vernengo A   +9 more
europepmc   +1 more source

The Inuence of Cross-Section Shape of the Car Roof Rail on the Quqsi-Dynamic Buckling Modes [PDF]

open access: yes, 2013
This paper presents the results of numerical analysis of the aluminium profiles subjected to dynamic, of different time duration impulse loading. The analysis includes the change in cross–section of the roof rail, ranging from the open ”C profile ...
Mróz, Andrzej
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Review on Stress-Strain Rate Controllable Loading of Functionally Graded Materials

open access: yesGaoya wuli xuebao
Given the dependence that key material dynamic properties in critical fields (e.g., national defense security and high-end manufacturing) have on stress-strain rate-controlled loading.
Chengcheng GUO   +6 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

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