Mechanical performance under dynamic loading of rubberized asphalt mixtures with highly-porous vesicular aggregate. [PDF]
Sci Rep, 2022 Franesqui MA, Yepes J, Gallego J.
europepmc +1 more source
Dynamic tensile behaviour and crack propagation of coal under coupled static-dynamic loading
, 2020 Hao Xianjie +6 more
semanticscholar +1 more source
Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
FEBS Open Bio, EarlyView.Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
Dynamic loading leads to increased metabolic activity and spatial redistribution of viable cell density in nucleus pulposus tissue. [PDF]
JOR Spine, 2023 Salzer E +4 more
europepmc +1 more source
MOD-1 WTG dynamic analysis [PDF]
An analysis of the MOD-1 2000 kW horizontal axis wind turbine was given. The MOD-1 design was briefly described, and the analysis used to evaluate the dynamic loads and structural interactions is discussed. The resonant frequency placement, the treatment
Stahle, C. V., Jr.
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, EarlyView.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Experimental Investigation of Pre-Flawed Rocks under Dynamic Loading: Insights from Fracturing Characteristics and Energy Evolution. [PDF]
Materials (Basel), 2022 Zhao G +5 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Frequency response characteristics and failure model of single-layered thin plate rock mass under dynamic loading. [PDF]
Sci Rep, 2022 Li F +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source