Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Numerical study of interstitial fluid flow behavior in osteons under dynamic loading. [PDF]
Liu T, Xiong B, Cui X, Zhang C.
europepmc +1 more source
Energy and Vibration Absorption Characteristics of Damping Holes under Explosion Dynamic Loading. [PDF]
Li Z, Wang L, Liang J, Zhang J, Zhang Q.
europepmc +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Study on the degradation mechanism of mechanical properties of red sandstone under static and dynamic loading after different high temperatures. [PDF]
Lin H, Liu W, Zhang D, Chen B, Zhang X.
europepmc +1 more source
Ion release from three different dental alloys - effect of dynamic loading and toxicity of released elements. [PDF]
Haugli KH, Syverud M, Samuelsen JT.
europepmc +1 more source
software release of dynamic load balancing using teams of subtrees, functionality as described in WP 3.a and WP 3 ...
openaire +1 more source
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: finite element analysis under dynamic loading. [PDF]
Jia Z +5 more
europepmc +1 more source
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer +5 more
wiley +1 more source

