Results 81 to 90 of about 7,484,360 (335)
Response of pile-guided floats subjected to dynamic loading [PDF]
, 2013 Pile-guided floats can be a desirable alternative to stationary berthing structures. Both floats and guide piles are subjected to time varying (dynamic) forces such as wind-generated waves and impacts from vessels.
Quan, Zhili, 权致力
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
LONGITUDINAL NON-STATIONARY MOTIONS OF MAGLEV TRAIN
Nauka ta progres transportu, 2019 Purpose. The quality of passenger’s and good’s transportation by a magnetically levitated train (MLT) is a key criterion for evaluating its consumer properties.
V. O. Polyakov, N. M. Khachapuridze
doaj +1 more source
Dynamically Loading Mobile/Cloud Assemblies [PDF]
, 2017 Distributed applications that span mobile devices, computing clusters, and cloud services, require robust and flexible mechanisms for dynamically loading code. This paper describes lady: a system that augments the .net platform with a highly reliable mechanism for resolving and loading assemblies, and arranges for safe execution of partially trusted ...
Pettersen, Robert +3 more
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Response of Pile-Guided Floats Subjected to Dynamic Loading [PDF]
, 2014 INE/AUTC 14.10 (Volume 1) and INE/AUTC 14.10b (Volume II ...
Metzger, Andrew, Quan, Zhili
core
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Effects of Principal Stress Rotation on the Fluid-Induced Soil Response in a Porous Seabed
Journal of Marine Science and Engineering, 2019 Principal stress rotation (PSR) is an important feature for describing the stress status of marine sediments subject to cyclic loading. In this study, a one-way coupled numerical model that combines the fluid model (for wave−current interactions ...
Zhengxu Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source