Results 161 to 170 of about 4,613,401 (236)

cGMP Signaling in Arterioles Revealed by FRET‐Based Real‐Time Measurement in Mice In Vivo

open access: yesActa Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT cGMP evokes arteriolar vasorelaxation and is generated in smooth muscle by the soluble guanylyl cyclase (sGC) stimulated by endothelial NO. Phosphodiesterases (PDEs) degrade cGMP and may contribute in diameter regulation. We examined arteriolar cGMP levels in real‐time in vivo upon NO and acetylcholine (ACh) and effects of PDE inhibition ...
Lukas Thiele   +6 more
wiley   +1 more source

Accelerating Sustainable Epoxy Resin Development Through Bayesian Optimization and Inverse Design

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 37, October 5, 2026.
Development of a machine learning framework for the optimization of the Tg of partially bio‐based epoxy resin formulations in a 13‐component design space using Bayesian optimization, active learning, random design, and inverse design. The results show that the BO effectively navigates high‐dimensional formulation spaces, and the final ML model could ...
Natalie Wunder   +3 more
wiley   +1 more source

Endothermy, neuron counts, and other issues: Further remarks on neurocognitive evolution in fossil vertebrates

open access: yesThe Anatomical Record, Volume 309, Issue 10, Page 2560-2573, October 2026.
Abstract Last year, we challenged the view that large‐bodied theropod dinosaurs such as Tyrannosaurus rex resembled primates in cognition and behavior, a proposition made by Herculano‐Houzel in 2023. More recently, Jensen et al. have criticized our work on this topic, raising methodological and conceptual issues.
Kai R. Caspar   +5 more
wiley   +1 more source

In Situ Imaging for Monitoring Biomass Content and Pellet Size in Submerged Filamentous Stirred‐Tank Cultivation

open access: yesBiotechnology Journal, Volume 21, Issue 10, October 2026.
Graphical Abstract and Lay Summary Noninvasive imaging through a stirred‐tank reactor wall enabled time‐resolved monitoring of biomass and projected pellet size. Model‐sphere validation identified size‐ and concentration‐dependent biases; in Aspergillus oryzae cultivation, luminosity followed biomass, pellet‐size increases coincided with Zn2 ...
Lukas Hartmann   +4 more
wiley   +1 more source

Multispectral Analysis Graphical User Interface for Ratiometric Analysis and Background Correction

open access: yesChemistry–Methods, Volume 6, Issue 10, October 2026.
This article describes multispectral analysis graphical user interface, an open‐source, cross‐platform graphical application for highly modular batch image analysis and visualization that requires no coding experience. With common image operations as a palette, users can define their own analysis pipeline (e.g., background subtraction into ...
Grayson R. Hoy, Caitlin M. Davis
wiley   +1 more source

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