Results 191 to 200 of about 2,899,528 (318)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Temperature-Controlled Chain Dynamics in Polyimide Doped with CoCl₂ Probed Using Dynamic Mechanical Analysis. [PDF]

Materials (Basel)
Ionita D, Cristea M, Sava I, Popescu MC, Dobromir M, Simionescu BC.   +5 more
europepmc   +1 more source

Comparison of Contemporary Elm (Ulmus spp.) and Degraded Archaeological Elm: The Use of Dynamic Mechanical Analysis Under Ambient Moisture Conditions. [PDF]

Materials (Basel), 2020
Spear MJ, Broda M.
europepmc   +1 more source

Self-powered pressure sensor based on the triboelectric effect and its analysis using dynamic mechanical analysis

Nano Energy, 2018
Cristobal Garcia, I. Trendafilova, R. Villoria, J. S. D. Río   +3 more
semanticscholar   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Structural, radiation shielding, thermal and dynamic mechanical analysis for waste rubber/EPDM rubber composite loaded with Fe₂O₃ for green environment. [PDF]

Sci Rep
AbdelKader MM, Abou-Laila MT, El-Deeb MSS, Taha EO, El-Deeb AS.   +4 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

A novel in-situ dynamic mechanical analysis for human plantar soft tissue: The device design, definition of characteristics, test protocol, and preliminary results. [PDF]

Heliyon
Wu L, Huang R, Tang L, Ning X, Zhu J, Ma X.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Nanoscale Rheology: Dynamic Mechanical Analysis over a Broad and Continuous Frequency Range Using Photothermal Actuation Atomic Force Microscopy. [PDF]

Macromolecules
Piacenti AR, Adam C, Hawkins N, Wagner R, Seifert J, Taniguchi Y, Proksch R, Contera S.   +7 more
europepmc   +1 more source