Results 51 to 60 of about 40,631 (197)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Analyzing Nonlinear Dynamics via Data-Driven Dynamic Mode Decomposition-Like Methods

open access: yesComplexity, 2018
This article presents a review on two methods based on dynamic mode decomposition and its multiple applications, focusing on higher order dynamic mode decomposition (which provides a purely temporal Fourier-like decomposition) and spatiotemporal Koopman ...
Soledad Le Clainche, José M. Vega
doaj   +1 more source

Tensor-based dynamic mode decomposition [PDF]

open access: yesNonlinearity, 2018
Dynamic mode decomposition (DMD) is a recently developed tool for the analysis of the behavior of complex dynamical systems. In this paper, we will propose an extension of DMD that exploits low-rank tensor decompositions of potentially high-dimensional data sets to compute the corresponding DMD modes and eigenvalues.
Klus, Stefan   +3 more
openaire   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Analysis of Pressure Fluctuation Characteristics of Central Swirl Combustors Based on Empirical Mode Decomposition

open access: yesSensors, 2022
In order to study the characteristics of pressure fluctuation during unstable combustion, experimental studies had been conducted on the mechanism model of the swirl combustor and the industrial swirl combustor.
Xuhuai Wang   +4 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Preconditioned dynamic mode decomposition and mode selection algorithms for large datasets using incremental proper orthogonal decomposition

open access: yesAIP Advances, 2017
In this letter, we propose a simple and efficient framework of dynamic mode decomposition (DMD) and mode selection for large datasets. The proposed framework explicitly introduces a preconditioning step using an incremental proper orthogonal ...
Yuya Ohmichi
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Data-Driven Pulsatile Blood Flow Physics with Dynamic Mode Decomposition

open access: yesFluids, 2020
Dynamic mode decomposition (DMD) is a purely data-driven and equation-free technique for reduced-order modeling of dynamical systems and fluid flow. DMD finds a best fit linear reduced-order model that represents any given spatiotemporal data.
Milad Habibi   +2 more
doaj   +1 more source

Dynamic Mode Decomposition for Compressive System Identification [PDF]

open access: yesAIAA Journal, 2020
19 pages, 11 ...
Bai, Zhe   +4 more
openaire   +3 more sources

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