Results 51 to 60 of about 43,720 (247)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Dynamic Mode Decomposition via Polynomial Root-Finding Methods
MathematicsDynamic mode decomposition (DMD) is a powerful data-driven tool for analyzing complex systems that has gained significant attention in various scientific and engineering disciplines.
Gyurhan Nedzhibov
doaj +1 more source
Dynamic mode decomposition for analytic maps
Communications in Nonlinear Science and Numerical Simulation, 2020 14 pages.
Julia Slipantschuk +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Tensor Dynamic Mode Decomposition
IEEE Signal Processing Letters6 pages, 4 figures, 1 ...
Ziqin He +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Data-Driven Pulsatile Blood Flow Physics with Dynamic Mode Decomposition
Fluids, 2020 Dynamic mode decomposition (DMD) is a purely data-driven and equation-free technique for reduced-order modeling of dynamical systems and fluid flow. DMD finds a best fit linear reduced-order model that represents any given spatiotemporal data.
Milad Habibi +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Dynamic Mode Decomposition with Control Liouville Operators
IFAC-PapersOnLine, 2021 This paper builds the theoretical foundations for dynamic mode decomposition (DMD) of control-affine dynamical systems by leveraging the theory of vector-valued reproducing kernel Hilbert spaces (RKHSs). Specifically, control Liouville operators and control occupation kernels are introduced to separate the drift dynamics from the input dynamics.
Joel A. Rosenfeld +1 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source