Results 1 to 10 of about 1,501,808 (120)

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action

open access: yesNature Communications, 2021
HER2 acts an oncogenic driver in numerous cancers. Here, the authors design an anti-HER2 biparatopic and tetravalent IgG fusion with inhibitory effects in a xenograft model.
Florian Kast   +14 more
doaj   +1 more source

Back analysis of dynamic parameters of high earth-rock dam materials under weak earthquakes

open access: yesYantu gongcheng xuebao, 2020
In the case of weak earthquakes, a back analysis model considering interaction and radiation damping effects is proposed for dynamic parameters of earth-rock dams.
WANG Mao-hua 1, 2, CHI Shi-chun 1, 2, XIANG Biao 3, ZHOU Xiong-xiong 1, 2
doaj   +1 more source

Dynamic Simulation and Parameter Analysis of Weaved Composite Material for Unmanned Aerial Vehicle Parachute Recovery in Deployment Phase

open access: yesCrystals, 2022
Aiming at the parachute recovery of fixed-wing unmanned aerial vehicles, a method of parachute deployment by tractor rocket is proposed. First, the tensile tests were carried out on high-strength polyethylene and brocade silk-weaved composite materials ...
Wenhui Shi   +7 more
doaj   +1 more source

Modeling the public health impact of different meningococcal vaccination strategies with 4CMenB and MenACWY versus the current toddler MenACWY National Immunization Program in Chile

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Invasive meningococcal disease (IMD) is an uncommon yet unpredictable, severe, and life-threatening disease with the highest burden in young children. In Chile, most IMD is caused by meningococcal serogroup B (MenB) and W (MenW) infection. In response to
María Gabriela Graña   +6 more
doaj   +1 more source

Development of a Dynamic Model for Calculating the Kinematic Error and Evaluating Its Effect on the Efficiency of Planetary Mechanisms with Rolling Bodies

open access: yesМеханика машин, механизмов и материалов, 2023
When studying the characteristics of the mechanisms of small-sized drives, an important task is to develop ways to increase the efficiency of the mechanism.
Alexander V. Kapitonov
doaj   +1 more source

Influence of vehicle acceleration intensity on dual-mass flywheel elements and transmission load

open access: yesTransport Technologies, 2022
Modern high-torque low-speed internal combustion engines (ICEs) generate torsional vibrations close in disturbance frequency to gearboxes natural oscillation frequencies. Effective absorption of such oscillations requires a new torsional vibration damper
Bohdan Kindratskyy   +2 more
doaj   +1 more source

Optimization of Offshore Wind Power Generation in Response to the 2022 Extreme Drought in Portugal

open access: yesEnergies, 2023
Portugal, in line with the European Union, is aiming for carbon neutrality by 2050 (Net Zero), which implies a transition to sustainable energy sources. Climate change is all too evident, as extreme weather periods are occurring in a cyclical manner with
Fernando M. Camilo   +3 more
doaj   +1 more source

An Integrated Dynamic Model and Optimized Fuzzy Controller for Path Tracking of Deep-Sea Mining Vehicle

open access: yesJournal of Marine Science and Engineering, 2021
The capability of path tracking largely determines the operational efficiency of deep-sea mining vehicles. In this paper, the relationships of vehicle–sediment mechanical interaction were obtained by sinkage and shear tests.
Yu Dai, Cong Xue, Qiao Su
doaj   +1 more source

Dynamic model of a harvester equipped with a rope anchor system during logging operations on a steep slope [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета
The efficiency of using logging machines for work in mountainous or hilly areas characterized by the presence of steep slopes depends on many factors, among which the quantitative parameters of the dynamic state of both the harvester itself and the ...
Lagerev A.V.   +2 more
doaj   +1 more source

Numerical simulation of dynamic processes during operation of emergency brake of tunnel escalators [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета
The emergency brake is an essential element of the escalator safety system, designed to prevent the negative consequences of emergency situations. However, due to the very rare operation of this mechanism, the effect of dynamic loads on its elements has ...
Kozlov M.N.
doaj   +1 more source

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