Results 251 to 260 of about 12,701,784 (312)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

In Vitro Dynamic Model Evaluation of Meropenem Alone and in Combination with Avibactam Against Carbapenemase-Producing Klebsiella pneumoniae. [PDF]

Pharmaceuticals (Basel)
Strukova EN, Portnoy YA, Golikova MV, Zinner SH.   +3 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A dynamic model of gene activation in response to hypoxia accounting for both HIF-1 and HIF-2. [PDF]

Brief Funct Genomics
Cabaj A, Charzyńska A, Moszyńska A, Jaśkiewicz M, Bartoszewski R, Dąbrowski M.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evaluating the effectiveness of different intervention measures for an outbreak of mycoplasma pneumoniae in hangzhou based on a dynamic model. [PDF]

Sci Rep
Xu L, Lu R, Wang C, Zhou J, Su Z, Wu H.
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Shock response regulation effects and nonlinear dynamic model of lead-cone waveform generator. [PDF]

Heliyon
Liu C, Wu Y, Wen J, Wu B, Xu F, Yuan K.
europepmc   +1 more source

Multi-region infectious disease prediction modeling based on spatio-temporal graph neural network and the dynamic model. [PDF]

PLoS Comput Biol
Wang X, Jin Z.
europepmc   +1 more source

An individual-based dynamic model to assess interventions to mitigate opioid overdose risk. [PDF]

Harm Reduct J
Gallant K, Lukeman R.
europepmc   +1 more source