Results 251 to 260 of about 2,018,771 (302)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Investigating new drugs from marine seaweed metabolites for cervical cancer therapy by molecular dynamic modeling approach. [PDF]

Sci Rep
Islam SI, Ahmed SS, Mahfuj S, Das G, Tareq MMI, Almehmadi M, Allahyani M, Alsiwiehri N, Biswas P, Hasan MN, Ahammad F.   +10 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Towards Sustainable and Dynamic Modeling Analysis in Korean Pine Nuts: An Online Learning Approach with NIRS. [PDF]

Foods
Li H, Jiang D, Dong W, Cheng J, Zhang X.
europepmc   +1 more source

Computational Fluid Dynamic Modeling and Experimental Validation of Adsorption-Based CO₂ Separation From Flue Gas Using Porous Activated Carbon. [PDF]

ACS Omega
Aliyu M, Abdelnaby MM, Bakare AI, Abdalla MA, Zentou H, Nemitallah MA.   +5 more
europepmc   +1 more source

Type-3 fuzzy logic and Lyapunov approach for dynamic modeling and analysis of financial markets. [PDF]

Heliyon
Yan SR, Mohammadzadeh A, Ghaderpour E.
europepmc   +1 more source

Routine immunization against Streptococcus pneumoniae and Haemophilus influenzae type B and antibiotic consumption in India: a dynamic modeling analysis. [PDF]

Lancet Reg Health Southeast Asia
Kumar CK, Gleason AC, Parameswaran GG, Summan A, Klein E, Laxminarayan R, Nandi A.   +6 more
europepmc   +1 more source

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Modeling Dynamics in Crowdfunding

Marketing Science, 2020
This paper investigates the underlying mechanisms of crowdfunding behavior (forward-looking delaying investment behavior and social interactions), which lead to the crowdfunding dynamics.
Chul Kim, P. K. Kannan 0001, Michael Trusov, Andrea Ordanini   +3 more
openaire   +2 more sources

Dynamic topic models

Proceedings of the 23rd international conference on Machine learning - ICML '06, 2006
A family of probabilistic time series models is developed to analyze the time evolution of topics in large document collections. The approach is to use state space models on the natural parameters of the multinomial distributions that represent the topics.
David M. Blei, John D. Lafferty
openaire   +1 more source

Dynamic Model of Excavator

Journal of Aerospace Engineering, 1993
Automation of excavation work calls for a robotic system able to perform the planned digging work that is responsive to interaction forces experienced during excavation. The development of automated excavation control methods requires a dynamic model to describe the evolution of the excavator motion with time.
Vähä, Pentti, Skibniewski, Miroslaw
openaire   +2 more sources