Results 111 to 120 of about 4,044,594 (272)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Parameter Estimation for an Electric Arc Furnace Model Using Maximum Likelihood
TecnoLógicas, 2012 In this paper, we present a methodology for estimating the parame-ters of a model for an electrical arc furnace, by using maximum likelihood estimation.
Jesser J. Marulanda-Durango +2 more
doaj
Relaxation oscillations in the Darie wind power plant model
Вестник Самарского университета: Естественнонаучная серияThe article discusses the mathematical model of the Daria small wind power plant. This installation is a type of vertical axis wind turbine named after its inventor, Georges Jean Marie Darrieux.
Alena S. Kirsanova
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Research on Hopf bifurcation of vehicle air compressor system with single-pendulum TMD
Electronic Research ArchiveNonlinear tuned mass dampers (TMDs) are widely recognized for their superior damping perfor-mance, which stems from their broad damping bandwidth. In this study, we propose a sin-gle-pendulum TMD for application in vibration absorption within train ...
Danyang Wang, Ning Chen
doaj +1 more source
Dynamic models in space and time [PDF]
This paper presents a first-order autoregressive distributed lag model in both space and time. It is shown that this model encompasses a wide series of simpler models frequently used in the analysis of space-time data as well as models that better fit ...
Elhorst, J.P.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source