Results 181 to 190 of about 4,044,594 (272)

Dynamic models of obstructive sleep apnea provide robust prediction of respiratory event timing and a statistical framework for phenotype exploration. [PDF]

Sleep, 2022
Chen S, Redline S, Eden UT, Prerau MJ.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ziegler and Nichols meet Kermack and McKendrick: Parsimony in dynamic models for epidemiology. [PDF]

Comput Chem Eng, 2022
Nikolaou M.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Heterogeneity in suicide risk: Evidence from personalized dynamic models. [PDF]

Behav Res Ther
Coppersmith DDL, Kleiman EM, Millner AJ, Wang SB, Arizmendi C, Bentley KH, DeMarco D, Fortgang RG, Zuromski KL, Maimone JS, Haim A, Onnela JP, Bird SA, Smoller JW, Mair P, Nock MK.   +15 more
europepmc   +1 more source

How reliable are estimates of key parameters in viral dynamic models?

, 2023
Zitzmann C, Ke R, Ribeiro RM, Perelson AS.   +3 more
europepmc   +1 more source

Development and validation of dynamic models to predict postdischarge mortality risk in patients with acute myocardial infarction: results from China Acute Myocardial Infarction Registry. [PDF]

BMJ Open, 2023
Lv J, Wang C, Gao X, Yang J, Zhang X, Ye Y, Dong Q, Fu R, Sun H, Yan X, Zhao Y, Wang Y, Xu H, Yang Y, China Acute Myocardial Infarction Registry study group.   +14 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Informing policy via dynamic models: Cholera in Haiti. [PDF]

PLoS Comput Biol
Wheeler J, Rosengart A, Jiang Z, Tan K, Treutle N, Ionides EL.   +5 more
europepmc   +1 more source

Dynamic models of stress-smoking responses based on high-frequency sensor data. [PDF]

NPJ Digit Med, 2021
Hojjatinia S, Daly ER, Hnat T, Hossain SM, Kumar S, Lagoa CM, Nahum-Shani I, Samiei SA, Spring B, Conroy DE.   +9 more
europepmc   +1 more source