Results 41 to 50 of about 3,963,463 (245)

Baseline and long-term frailty transitions and rapid estimated glomerular filtration rate decline: evidence from two large population-based studies

open access: yesRenal Failure
Frailty is widely recognized to be associated with kidney function decline, but its longitudinal relationship with rapid estimated glomerular filtration rate (eGFR) decline remains unclear.
Ying Deng   +8 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Observations of an Energetically Isolated Quiet Sun Transient: Evidence of Quasi-Steady Coronal Heating [PDF]

open access: yes, 2015
Increasing evidence for coronal heating contributions from cooler solar atmospheric layers, notably quiet Sun (QS) conditions, challenges standard solar atmospheric descriptions of bright transition region (TR) emission. As such, questions to the role of
Chesny, David L.   +2 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Robust control of a bimorph mirror for adaptive optics system [PDF]

open access: yes, 2008
We apply robust control technics to an adaptive optics system including a dynamic model of the deformable mirror. The dynamic model of the mirror is a modification of the usual plate equation. We propose also a state-space approach to model the turbulent
Arzelier, Denis   +3 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dynamics of Wetting Fronts in Porous Media

open access: yes, 1998
We propose a new phenomenological approach for describing the dynamics of wetting front propagation in porous media. Unlike traditional models, the proposed approach is based on dynamic nature of the relation between capillary pressure and medium ...
A. E. Scheidegger   +31 more
core   +1 more source

On the interpretation and identification of dynamic Takagi-Sugenofuzzy models [PDF]

open access: yes, 2000
Dynamic Takagi-Sugeno fuzzy models are not always easy to interpret, in particular when they are identified from experimental data. It is shown that there exists a close relationship between dynamic Takagi-Sugeno fuzzy models and dynamic linearization ...
Johansen, T.A.   +2 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cytocompatible Enzymatic Hydrogelation of Phenylboronic Acid‐Alginate via H2O2‐Triggered Deboronation

open access: yesMacromolecular Materials and Engineering
This study aims to establish a functional hydrogelation system that integrates both dynamic and static properties without the use of additives. Given the increasing demand for biocompatible and mechanically tunable hydrogels, a hydrogelation strategy to ...
Ryota Goto, Shinji Sakai
doaj   +1 more source

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