Results 101 to 110 of about 446,026 (280)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Demo: Snap – Rapid Sensornet Deployment with a Sensornet Appstore [PDF]

, 2011
Despite ease of deployment being seen as a primary advantage of sensor networks, deployment remains difficult. We present Snap, a system for rapid sensornet deployment that allows sensor networks to be deployed, positioned, and reprogrammed through a
Dunkels, Adam, Duquennoy, Simon, Wirström, Niklas   +2 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Evaluating Network Performance in a Web-Based Augmented Reality System for Lipmatte Color Recommendation

Journal of Computing Research and Innovation
This study presents the Augmented Reality (AR) Lipmatte Recommendation System aimed at enhancing user experience and optimizing performance within the beauty industry.
Zulfikri Paidi, Nurhanna Md Abd Wahid, Nurzaid Muhd Zain, Mahfudzah Othman   +3 more
doaj   +1 more source

Dynamic load management for IMS networks using network function virtualization

, 2021
Long Term Evolution (LTE) access technology has become a de facto standard to meet the unprecedented mobile traffic increase. LTE, which has an all IP based architecture, uses IP Multimedia Subsystem (IMS) at the core network for delivering and managing IP multimedia services. IMS systems has several functions like P-CSCF, I-CSCF, S-CSCF and HSS.
openaire   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Structural Damage Detection under Short Time Load Using Cascade-Forward Network [PDF]

Journal of Rehabilitation in Civil Engineering
Damage identification in structures is one of the most important problems in structural engineering because early damage detection prevents a catastrophic event in structures.
Seyed Sina Kourehli
doaj   +1 more source

Fatigue analysis of catenary contact wires for high speed trains [PDF]

, 2011
The fatigue fracture is one of the most critical failures which may occur on the high speed network because it is undetectable and it has a huge impact on traffic disruption.
BALMES, Etienne, MAITOURNAM, Habibou, MASSAT, Jean-Pierre, NGUYEN TAJAN, T.M.L.   +3 more
core