Results 111 to 120 of about 446,026 (280)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
SensorsDistributed optical fibre sensing (DOFS)-based strain measurement systems are now routinely deployed across infrastructure health monitoring applications.
Nigel J. Cassidy +4 more
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
EnergiesThe maritime shipping sector is a major contributor to greenhouse gas emissions, particularly in coastal regions. In response, the adoption of electric ferries powered by renewable energy and supported by battery storage technologies has emerged as a ...
Rajib Baran Roy +2 more
doaj +1 more source
Application of Angle Related Cost Function Optimization for Dynamic Path Planning Algorithm
Algorithms, 2018 In recent years, Intelligent Transportation Systems (ITS) have developed a lot. More and more sensors and communication technologies (e.g., cloud computing) are being integrated into cars, which opens up a new design space for vehicular-based ...
Mingbin Zeng +3 more
doaj +1 more source
Dynamic load balancing in energy packet networks
Performance EvaluationEnergy Packet Networks (EPNs) model the interaction between renewable sources generating energy following a random process and communication devices that consume energy. This network is formed by cells and, in each cell, there is a queue that handles energy packets and another queue that handles data packets.
Bušić, Ana +2 more
openaire +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Combined CNN-LSTM Network for State-of-Charge Estimation of Lithium-Ion Batteries
IEEE Access, 2019 State-of-charge (SOC), which indicates the remaining capacity at the current cycle, is the key to the driving range prediction of electric vehicles and optimal charge control of rechargeable batteries.
Xiangbao Song +3 more
doaj +1 more source
Analysis of dynamic system optimum and externalities with departure time choice [PDF]
, 2006 This paper aims to analyse the dynamic system optimal assignment with departure time choice, which is an important, yet underdeveloped area. The main contribution of this paper is the necessary conditions and the sensitivity analysis for dynamic system
Chow, A.H.F.
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