Results 31 to 40 of about 95,886 (246)

Modular composition of gene transcription networks. [PDF]

open access: yesPLoS Computational Biology, 2014
Predicting the dynamic behavior of a large network from that of the composing modules is a central problem in systems and synthetic biology. Yet, this predictive ability is still largely missing because modules display context-dependent behavior.
Andras Gyorgy, Domitilla Del Vecchio
doaj   +1 more source

The robust network loading problem with dynamic routing [PDF]

open access: yesComputational Optimization and Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +4 more sources

A Global Sensitivity Analysis of Dynamic Loading and Route Selection Parameters on Network Performances

open access: yesJournal of Advanced Transportation, 2018
We conduct a Global Sensitivity Analysis (GSA) of urban-scale network performances to parameters representing a wide range of realistic dynamic loadings, decomposed in a choice of OD matrix, routing alternatives, and paths flow distribution.
Charlotte Duruisseau, Ludovic Leclercq
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

DYNAMIC METHOD OF LOAD BALANCING OF DATA CENTERS TAKING INTO ACCOUNT THE FRACTAL PROPERTIES OF NETWORK TRAFFIC

open access: yesСовременная наука и инновации, 2022
An approach to the development and study of a load balancing system for data centers (DC) taking into account the fractal properties of network traffic is proposed. The fractal properties of network traffic make it possible to predict, with a fairly high
G. I. Linets   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Molecular dynamics simulations of dynamics mechanical behavior and interfacial microstructure evolution of Ni-based single crystal superalloys under shock loading

open access: yesJournal of Materials Research and Technology, 2021
In this paper, molecular dynamics simulations are performed to study the dynamic mechanical response and microstructural evolution of Ni-based single crystal superalloys under different shock velocities. The results show that when the shock velocity (Up ≤
Bin Chen, Wen-Ping Wu
doaj   +1 more source

Modelling dynamic network loading ontransportation networks through a continuous [PDF]

open access: yesMathematical Modelling of Systems, 1996
The efforts spent by researchers in the last few years in traffic modelling have been focused on the modelization of dynamic behaviour of the several components making up a transportation system.In the field of traffic assignment, a large number of models and procedures have been proposed in order to perform Dynamic Network Loading (DNL), that is the ...
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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