Results 51 to 60 of about 793,158 (268)

An Adaptive Damping Network Designed for Strapdown Fiber Optic Gyrocompass System for Ships

open access: yesSensors, 2017
The strapdown fiber optic gyrocompass (strapdown FOGC) system for ships primarily works on external horizontal damping and undamping statuses. When there are large sea condition changes, the system will switch frequently between the external horizontal ...
Jin Sun   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Simulation and Performance Analysis of Large-scale Wind Turbine Based on FAST and Simulink

open access: yesKongzhi Yu Xinxi Jishu, 2012
Rotor system, drive chain system, generator system and control system of large-scale wind turbine are described in this paper. Taking a 5 MW doubly fed wind turbine as a research object, the model of wind turbine is established through FAST software and ...
LIU Hongwen   +5 more
doaj  

Design and Analysis of Novel Linear Oscillating Loading System

open access: yesApplied Sciences, 2019
Although linear motor has vital and potential applications in air compressors, hydraulic pumps, earphones and electric vehicles because of its good reliability, high power density and convenient maintenance, most researchers rarely concentrate on the ...
Zongxia Jiao   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Performance Measures for Dynamic Environments [PDF]

open access: yes, 2002
This article investigates systematically the utility of performance measures in non-stationary environments. Three characteristics for describing the goals of a dynamic adaptation process are proposed: accuracy, stability, and recovery. This examination underpins the usage of the best fitness value as a basis for measuring the three characteristics in ...
openaire   +1 more source

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