Results 171 to 180 of about 10,040 (298)

Computational experience with a branch-and-bound procedure for the resource-constrained project scheduling problem with generalized precedence relations. [PDF]

open access: yes
In a previous paper (De Reyck and Herroelen, 1996a), we presented an optimal procedure for the resource-constrained project scheduling problem (RCPSP) with generalised precedence relations (further denoted as RCPSP-GPR) with the objective of minimizing ...
De Reyck, B, Herroelen, Willy
core  

Dynamically Changing Priorities Algorithm for CPU Scheduling

open access: yesJournal of Applied Sciences, 2006
M. Raghunadh Acharya   +3 more
openaire   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Dynamic Scheduling with a Genetic Algorithm and a Priority Rule

open access: yesProceedings of JSPE Semestrial Meeting, 2004
Eguchi, Toru   +2 more
openaire   +1 more source

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